Dublin has long been known as the European headquarters for big pharma giants, but a quieter revolution is happening in the city’s co-working spaces and university labs. The Irish capital has evolved into a premier hub for “MedTech 2.0”, a convergence of Ireland’s deep manufacturing heritage and its modern software prowess. Supported by aggressive funding from Enterprise Ireland and a rich talent pool from Trinity and UCD, these companies are solving deep clinical problems, from pathology bottlenecks to athletic performance.
Here are the 10 Dublin-based health-tech startups that are currently rewriting the rules of modern medicine.
LetsGetChecked
If there is a king of the Dublin health-tech hill, this is it. Founded in 2015 by Peter Foley, LetsGetChecked achieved unicorn status with a valuation exceeding $1 billion. They revolutionised healthcare access by allowing patients to test for over 30 different conditions, from diabetes and cholesterol to sexual health, from the privacy of their own homes. By owning the entire supply chain, including their own CLIA/CAP-accredited laboratories, they have removed the friction of doctor visits for millions of users. Their aggressive expansion strategy has seen them pivot from a pure D2C model to a major B2B player, acquiring companies like BioIQ and Veritas Genetics to bolster their genomics and population health capabilities for major US health plans.
Nuritas
While most companies discover drugs through trial and error, Nuritas discovers them through data. Founder Dr Nora Khaldi launched the company in 2014 with a vision to utilise artificial intelligence to identify bioactive peptides hidden within food. Their proprietary “Magnifier” platform analyses billions of molecules to find those with specific therapeutic benefits, effectively turning nature into a pharmacy. Backed by high-profile investors like U2’s Bono and having raised over $45 million in Series B funding, they have successfully commercialised ingredients like PeptAIde™ for inflammation and are currently collaborating with massive conglomerates like Nestlé and Pharmavite to create the next generation of scientifically validated functional ingredients.
Deciphex
Pathology is currently facing a global crisis as there are simply too many slides and not enough specialists to read them. Deciphex, founded by Donal O’Shea in 2017, is digitising this analogue workflow. Their AI-driven platform enables pathologists to review cases remotely and more efficiently than ever before, utilising algorithms to triage negative samples, allowing doctors to focus on the critical ones. The company operates through two main arms, Patholytix for pharmaceutical research and Diagnexia for clinical diagnostics. They recently solidified their market dominance by closing a massive €31 million Series C round in early 2025, capital primarily earmarked to aggressively expand their Diagnexia consult service across the US healthcare system.
Spectrum.Life
Corporate wellness used to mean a free bowl of fruit in the canteen. Spectrum.Life has transformed it into a clinical-grade digital health suite. Founded by Stuart McGoldrick in 2018, the company provides mental health support, GP services, and wellbeing coaching to over 2,500 clients, including major insurers and universities. They differentiate themselves by offering full-stack care, not just signposting users to help, but actually providing the therapy and medical consultations in-app via their own employed clinicians. Their growth has been explosive, serving millions of users and capped by a recent €17 million funding round to drive their expansion across the UK and Europe.
Hexis
Fresh off their win as the Grand Prix champion at the 2025 National Startup Awards, Hexis is the new darling of the Dublin sports-tech scene. Co-founded by Dr David Dunne and Dr Samuel Impey, the platform offers “Carb Coding”, which is a personalised nutrition system that adapts to an athlete’s workout intensity in real-time. Instead of static diet plans, Hexis integrates with wearables like Garmin and Apple Health to tell you exactly what to eat and when, optimising performance and recovery. It’s essentially a digital nutritionist for the elite athlete, relying on predictive metabolic models rather than generic guidelines, and is already in use by Olympic medalists and professional rugby teams.
Output Sports
Elite sports science used to require a laboratory full of force plates and a PhD to operate. Output Sports shrank that lab into a single sensor that fits in your pocket. Spinning out of UCD’s data analytics hub, founders Dr Martin O’Reilly, Dr Darragh Whelan, and Julian Eberle have built the “Swiss Army Knife” of athlete testing. Their single sensor unit can measure over 150 metrics, including power, speed, mobility, and strength, instantly. Their tech has been adopted by over 400 professional teams, including organisations in the Premier League, NBA, and NFL, allowing coaches to democratise elite-level performance data without the six-figure equipment costs.
xWave Technologies
The waiting list for a radiology scan in Ireland can be months long, often due to inefficient referral systems, where up to 30% of requests are inappropriate or lack necessary information. xWave Technologies, founded by Mitchell O’Gorman in 2020, acts as an air traffic control system for radiology. Their smart referral platform, built in collaboration with the European Society of Radiology, ensures doctors order the right scan for the patient the first time. They recently participated in a significant €9.1 million Disruptive Technologies Innovation Fund (DTIF) project, highlighting their critical role in modernising the HSE and private hospital networks to reduce waiting list backlogs.
T-Pro
Burnout is the crisis defining modern medicine, and it’s often driven by the crushing weight of paperwork due to which doctors spend up to 50% of their day on documentation. T-Pro is handing that time back. Led by Jonathan Larbey, their AI-driven speech recognition engine allows clinicians to dictate complex medical notes directly into patient records with startling accuracy. This application understands medical context, accents, and terminology, and includes “ambient scribe” technology that can listen to a patient consultation and draft the notes automatically. Headquartered in Dublin, they support over 130,000 active users globally.
PatientMpower
Managing chronic lung conditions usually requires constant hospital visits. PatientMpower, founded by Eamonn Costello, moves that care into the home. Their platform connects to Bluetooth spirometers and pulse oximeters, allowing patients with Pulmonary Fibrosis, Cystic Fibrosis, or kidney transplant recipients to monitor their own vitals. The data is fed back to clinical teams in real-time, enabling early intervention before a patient’s condition deteriorates. Their technology is now reimbursed under Remote Patient Monitoring (RPM) codes in the US, solidifying it as a standard of care for major hospital systems, such as Mount Sinai in New York.
Akkure Genomics
The future of medicine lies in precision, but accessing clinical trials has historically been difficult, as over 80% of trials fail to meet their recruitment deadlines. Akkure Genomics, founded by Dr Oran Rigby and Dr Amy Hollingworth, utilises AI and blockchain technology to match patients with clinical trials that are relevant to their specific genomic makeup. Their Digital Twin technology empowers patients to take control of their own medical data and even get rewarded for sharing it with researchers via a tokenised system. By addressing the recruitment crisis for pharmaceutical companies, they are accelerating the development of life-saving therapies for rare diseases and cancer.
